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Product Literature

  • Product: Ponatinib

    Headline: Efficacy of ponatinib against ABL tyrosine kinase inhibitor-resistant leukemia cells

    Author: Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Kazuma Ohyashiki

  • Product: Bardoxolone methyl

    Headline: Bardoxolone methyl (BARD) ameliorates aristolochic acid (AA)-induced acute kidney injury through Nrf2 pathway

    Author: Juan Wu, Xinhui Liu, Jinjin Fan, Wenfang Chena, Juan Wang, Youjia Zeng, Xiaorang Feng, Xueqing Yu, Xiao Yang

  • Product: GDC0068

    Headline: Inhibition of Akt reverses the acquired resistance to sorafenib by switching protective autophagy to autophagic cell death in hepatocellular carcinoma

    Author: Bo Zhai, Fengli Hu, Xian Jiang, Jun Xu, Dali Zhao, Bing Liu, Shangha Pan, Xuesong Dong, Gang Tan, Zheng Wei, Haiquan Qiao, Hongchi Jiang, and Xueying Sun

  • Product: Docetaxel

    Headline: Biodegradable self-assembled nanoparticles of poly (d,l-lactide-co-glycolide)/hyaluronic acid block copolymers for target delivery of docetaxel to breast cancer

    Author: Jingbin Huang, He Zhang, Yuan Yu, Yan Chen, Dong Wang, Guoqing Zhang, Guichen Zhou, Junjie Liu, Zhiguo Sun, Duxin Sun, Ying Lu, Yanqiang Zhong

  • Product:BEZ235 & AZD6244

    Headline:    Role of survivin in EGFR inhibitor–induced apoptosis in non–small cell lung cancers positive for EGFR mutations

    Author:   Kunio Okamoto, Isamu Okamoto, Wataru Okamoto, Kaoru Tanaka, Ken Takezawa, Kiyoko Kuwata, Haruka Yamaguchi, Kazuto Nishio, and Kazuhiko Nakagawa

  • Product: CX-4945

    Headline: LYG-202 Augments Tumor Necrosis Factor-α-Induced Apoptosis via Attenuating Casein Kinase 2-Dependent Nuclear Factor-κB Pathway in HepG2 Cells

    Author: Fei-hong Chen, Na Lu, Hai-wei Zhang, Li Zhao, Li-cheng He, Hao-peng Sun, Qi-dong You, Zhi-yu Li, and Qing-long Guo

  • Product: SU6668

    Headline: Characterization of the Novel Broad-Spectrum Kinase Inhibitor CTx-0294885 As an Affinity Reagent for Mass Spectrometry-Based Kinome Profiling

    Author: Luxi Zhang, Ian P. Holmes, Falko Hochgr?fe, Scott R. Walker, Naveid A. Ali, Emily S. Humphrey, Jianmin Wu, Melanie de Silva, Wilhelmus J. A. Kersten, Theresa Connor, Hendrik Falk, Lynda Allan, Ian P. Street, John D. Bentley , Patricia A. Pilling , Brendon J. Monahan , Thomas S. Peat , and Roger J. Daly

  • Product: Perifosine

    Headline: Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro

    Author: Min-Bin Chen, Xiao-Yang Wu, Guo-Qing Tao, Chao-Ying Liu, Jian Chen, Li-Qiang Wang andPei-Hua Lu

  • Product: TAE684, crizotinib & BIBW2992

    Headline: Activation of HER Family Signaling as a Mechanism of Acquired Resistance to ALK Inhibitors in EML4-ALK–Positive Non–Small Cell Lung Cancer

    Author: Junko Tanizaki, Isamu Okamoto, Takafumi Okabe, Kazuko Sakai, Kaoru Tanaka, Hidetoshi Hayashi, Hiroyasu Kaneda, Ken Takezawa, Kiyoko Kuwata, Haruka Yamaguchi, Erina Hatashita, Kazuto Nishio, and Kazuhiko Nakagawa

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    Product Category

    PI3K/Akt/mTOR
    Cell Cycle/Checkpoint
    Angiogenesis/Tyrosine Kinase
    Apoptosis Pathway
    PARP/BET
    Aurora/Ksp Pathway
    MAPK Pathway
    Hormone Pathay
    Integrase/CCR5
    Proteases/HSP90/HSP70 Pathway
    Wnt/Hedgehog/Notch Pathway
    Jak/Stat Pathway
    Ca/cAMP/Lipid Signaling Pathway
    Neuro Signaling Pathway
    TGF-beta/Smad Signaling Pathway
    GPCR Pathway
    Ion channel Pathway
    Cytochrome P450 Pathway
    Others Pathway
    Intermediate